Vol. 7 (2026)

Alzheimer's disease in the Plasticene era: a clinicopathological update on the dual sequestration of amyloid and tau as hijacked innate immune responses
Michael A. S. Guth
Free Neuropathol 7:14 (2026)

An integrated multiscale imaging workflow to resolve intracellular co-pathology in human FFPE brain tissue
Sophie Schreiner, Mónica Miranda de la Maza, Morgane Darricau, David S. Bouvier
Free Neuropathol 7:13 (2026)

Unclassifiable senile plaques and extensive cerebral amyloid angiopathy involving spinal and bridging vessels in autopsied patients with Down syndrome
Hiroaki Miyahara, Yuichi Riku, Kumiko Yano, Yousuke Hidaka, Daisuke Tahara, Nao Tahara, Hideyuki Moriyoshi, Akio Akagi, Jun Sone, Hideki Hashidate, Akiyoshi Kakita, Yasushi Iwasaki
Free Neuropathol 7:12 (2026)

Brain extraction for fixed tissue banking: a technical report
Mads Wolf, Autumn Beck, Laura Paredes, Sarah Darcy, Alexander Parra, Gabriel A. Taylor, Macy Garrood, Emma L. Thorn, Claudia De Sanctis, John F. Crary, Kurt Farrell, Andrew McKenzie
Free Neuropathol 7:11 (2026)

Forensic neuropathology: 2026 update
Jakob Matschke
Free Neuropathol 7:10 (2026)

Published: 2026-01-08

Original Papers

An integrated multiscale imaging workflow to resolve intracellular co-pathology in human FFPE brain tissue

Sophie Schreiner, Mónica Miranda de la Maza, Morgane Darricau, David S. Bouvier

13
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Unclassifiable senile plaques and extensive cerebral amyloid angiopathy involving spinal and bridging vessels in autopsied patients with Down syndrome

Hiroaki Miyahara, Yuichi Riku, Kumiko Yano, Yousuke Hidaka, Daisuke Tahara, Nao Tahara, Hideyuki Moriyoshi, Akio Akagi, Jun Sone, Hideki Hashidate, Akiyoshi Kakita, Yasushi Iwasaki

12
- HTML
- PDF
Brain extraction for fixed tissue banking: a technical report

Mads Wolf, Autumn Beck, Laura Paredes, Sarah Darcy, Alexander Parra, Gabriel A. Taylor, Macy Garrood, Emma L. Thorn, Claudia De Sanctis, John F. Crary, Kurt Farrell, Andrew McKenzie

11
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Mass spectrometry imaging-based explainable machine learning reveals the biochemical landscapes of the mouse brain

Jacob Gildenblat, Jorunn Stamnas, Jens Pahnke

9
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Robust immunohistochemical detection of α-synuclein, tau and amyloid-β in human brain tissue archived for up to 78 years

Mie Kristine Just, Kristina Bang Christensen, Martin Wirenfeldt, Torben Steiniche, Laura Parkkinen, Liisa Myllykangas, Per Borghammer

6
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Reviews

Forensic neuropathology: 2026 update

Jakob Matschke

10
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Trends in neuropathology training in Sub-Saharan Africa – current curricula, resource gaps, and the potential of virtual microscopy and telemedicine

Habiblah Jagunmolu, Emmanuel Oyetola, Kamil Ajagbe, Samuel Oyelude, Muminat Jubreel, Oluwatosin Afolayan, Dorothy Abimbola, AbdurRoqeeb Ismail, Kaothar Oyeniran, Mukhtar Ibrahim, Bright Oguntola

2
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Opinion Pieces

Alzheimer's disease in the Plasticene era: a clinicopathological update on the dual sequestration of amyloid and tau as hijacked innate immune responses

Michael Guth

14
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Why it should be "Alzheimer disease" rather than "Alzheimer's disease"

Cinthya Aguero, C.Zachary Klein, Georg Haase

7
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Reflections

Reflections on a long career in Neuropathology

Michael Farrell

5
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Case Reports

Central nervous system schwannoma, VGLL-fused (EWSR1::VGLL1 fusion) with neuroblastoma-like cell dense areas in the frontal lobe of a young man with schwannomatosis due to a germline LZTR1 mutation

David G. Munoz, Sunit Das, Ju-Yoon Yoon, Robert Siddaway, Adrian Levine, Kenneth D. Aldape

1
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Letters

Bilateral optic perineuritis with vestibulocochlear involvement: revisiting a rarely performed biopsy

Katrina J. Jiang, Marianne E. Yassa, Saad Awan, Osama R. Elkadi

8
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Other

Form follows function: morphology as a map of mechanisms in neurodegenerative disease pathology

Edward B. Lee

4
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The shapes of brain waste: Mysteries of cellular remnant morphology in neurodegeneration

David V. Forrest

3
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Vol. 7 (2026)

Original Papers

An integrated multiscale imaging workflow to resolve intracellular co-pathology in human FFPE brain tissue

Unclassifiable senile plaques and extensive cerebral amyloid angiopathy involving spinal and bridging vessels in autopsied patients with Down syndrome

Brain extraction for fixed tissue banking: a technical report

Mass spectrometry imaging-based explainable machine learning reveals the biochemical landscapes of the mouse brain

Robust immunohistochemical detection of α-synuclein, tau and amyloid-β in human brain tissue archived for up to 78 years

Reviews

Forensic neuropathology: 2026 update

Trends in neuropathology training in Sub-Saharan Africa – current curricula, resource gaps, and the potential of virtual microscopy and telemedicine

Opinion Pieces

Alzheimer's disease in the Plasticene era: a clinicopathological update on the dual sequestration of amyloid and tau as hijacked innate immune responses

Why it should be "Alzheimer disease" rather than "Alzheimer's disease"

Reflections

Reflections on a long career in Neuropathology

Case Reports

Central nervous system schwannoma, VGLL-fused (EWSR1::VGLL1 fusion) with neuroblastoma-like cell dense areas in the frontal lobe of a young man with schwannomatosis due to a germline LZTR1 mutation

Letters

Bilateral optic perineuritis with vestibulocochlear involvement: revisiting a rarely performed biopsy

Other

Form follows function: morphology as a map of mechanisms in neurodegenerative disease pathology

The shapes of brain waste: Mysteries of cellular remnant morphology in neurodegeneration

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